1. 药材主信息
| 中文名称: | 制草乌 |
| 英文名称: | Prepared Kusnezoff Monkshood Root |
| 拉丁名称: | Radix Aconiti Kusnezoffii Preparata |
| 使用部位: | Radix Aconiti Kusnezoffii. |
| 功用: | Treatment of rheumatic and rheumatoid arthralgia, precordial and abdominal pain with cold sensation, abdominal colic caused by cold, anaethesia. |
| 适用症: | Treatment of rheumatic and rheumatoid arthralgia, precordial and abdominal pain with cold sensation, abdominal colic caused by cold, anaethesia. |
| 毒副作用: | Extremely Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 99-83-2 | 水芹烯 | - | 7460 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 652971-46-5 | (3R,4S)-4-苯基吡咯烷-3-羧酸 | (3R,4S)-4-Phenylpyrrolidine-3-carboxylic acid | 51051667 |
| 17430-12-5 | - | (3R,6E)-nerolidol | 11241545 |
| 562-74-3 | 4-松油醇 | 4-Terpineol, (+/-)- | 11230 |
| 100-52-7 | 苯甲醛 | Benzaldehyde | 240 |
| 79-92-5 | 莰烯 | Camphene | 6616 |
| 21368-68-3 | (±)-樟脑 | Camphor | 2537 |
| 507-70-0 | - | CID 44630107 | 44630107 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31678208 |
| CCL3 | G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3 | 17q12 | 25784697 |
| CD1A | CD1; FCB6; HTA1; R4; T6 | 1q23.1 | 25784697 |
| CD80 | B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7 | 3q13.33 | 25784697 |
| CD83 | BL11; HB15 | 6p23 | 25784697 |
| CD86 | B7-2; B7.2; B70; CD28LG2; LAB72 | 3q13.33 | 25784697 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 31678208 |
| CDH2 | CD325; CDHN; CDw325; NCAD | 18q12.1 | 31678208 |
| CNR2 | CB-2; CB2; CX5 | 1p36.11 | 31883107 |
| CSF2 | CSF; GMCSF | 5q31.1 | 25784697 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| HIV Infections | group | 22677126 |
| Multiple Myeloma | disease | 25697480 |
| Multiple Myeloma | disease | 23044853 |
| Pain | phenotype | 28396565 |
