1. 药材主信息
| 中文名称: | 玄参 |
| 英文名称: | Figwort Root |
| 拉丁名称: | Radix Scrophulariae |
| 使用部位: | root |
| 功用: | To reduce heat from blood, to nourish yin, to quench fire, and to counteract toxicity. |
| 适用症: | Heat entering construction-blood, generalized fever, vexation and thirst, crimson tongue, macular eruption, steaming bone taxation cough, vacuity vexation and insomnia, fluid damage and constipation, dry eyes with clouded flowery vision, swelling pain in throat, scrofula with phlegm node, sore toxin of welling abscess and flat abscess. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 73340-42-8 | - | (-)-Nissolin | 442812 |
| 52949-83-4 | - | (2S,3S,4R,5R,6S)-6-[[(4aS,7S,7aR)-7-hydroxy-7-methyl-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-1-yl]oxy]-2-(hydroxymethyl)oxane-2,3,4,5-tetrol | 6452750 |
| 66851-47-6 | - | 1,2-Benzenedi(carboxylic-14C)acid, dibutyl ester | 171810 |
| 705-15-7 | 2'-羟基-5'-甲氧基苯乙酮 | 2'-Hydroxy-5'-methoxyacetophenone | 69714 |
| 99282-79-8 | 2-(CARBOXYMETHYL-AMINO)-4-CHLORO-BENZOIC ACID | 2-((Carboxymethyl)amino)-4-chlorobenzoic acid | 11107141 |
| 645-08-9 | 异香草酸 | 3-Hydroxy-4-methoxybenzoic acid | 12575 |
| 150-19-6 | 间甲氧基苯酚 | 3-Methoxyphenol | 9007 |
| 99-93-4 | 4'-羟基苯乙酮 | 4'-Hydroxyacetophenone | 7469 |
| 50602-41-0 | - | 5-(2-Hydroxyethyl)-2-methoxyphenol | 10034991 |
| 59121-25-4 | 5-甲硫基戊腈 | 5-(Methylsulfanyl)pentanenitrile | 93320 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 21712449 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25950476 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24486741 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31406198 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30578827 |
| Cardiac Hypertrophy | phenotype | 26845648 |
| Cardiomegaly | phenotype | 26845648 |
| Chromosome Aberrations | group | 23701745 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Diabetes Mellitus, Experimental | disease | 25950476 |
| Hypercholesterolemia | disease | 31911244 |
