1. 药材主信息
| 中文名称: | 玄胡 |
| 英文名称: | root of corydalis |
| 拉丁名称: | Rhizoma Corydalis |
| 使用部位: | Corydalis turtschaninovii Bess. F. yanhusuo Y.H. Chou et C.C. Hsu. |
| 功用: | For stagnation of vital energy or blood stasis resulting in headache, chest pain, hypochondriac pain, epigastric pain, abdominal pain, backache, arthralgia, dysmenorrhea or trauma. Recently, alos used for angina pectoris, peptic ulcer and neuralgia. |
| 适用症: | 1. Its components d-corydaline and d1-tetrahydropalmatine are analgesics.2. Decreasing the secretion of gastric juice and the amount of pepsin. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 99-83-2 | 水芹烯 | - | 7460 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 106-22-9 | β-香茅醇 | - | 8842 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 2217-02-9 | - | (1R)-endo-(+)-Fenchyl alcohol | 6997371 |
| 80-57-9 | - | (1R,5S)-4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-one | 6973628 |
| 5655-61-8 | - | (2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl acetate | 44630108 |
| 17430-12-5 | - | (3R,6E)-nerolidol | 11241545 |
| 66851-47-6 | - | 1,2-Benzenedi(carboxylic-14C)acid, dibutyl ester | 171810 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31678208 |
| BAX | BCL2L4 | 19q13.33 | 21173435 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21173435 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 21173435 |
| CCL3 | G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3 | 17q12 | 25784697 |
| CD1A | CD1; FCB6; HTA1; R4; T6 | 1q23.1 | 25784697 |
| CD80 | B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7 | 3q13.33 | 25784697 |
| CD83 | BL11; HB15 | 6p23 | 25784697 |
| CD86 | B7-2; B7.2; B70; CD28LG2; LAB72 | 3q13.33 | 25784697 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 31678208 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cerebral Ischemia | disease | 30486272 |
| HIV Infections | group | 22677126 |
| Mouth Neoplasms | group | 21173435 |
| Multiple Myeloma | disease | 25697480 |
| Multiple Myeloma | disease | 23044853 |
| Pain | phenotype | 23791894 |
| Pain | phenotype | 28396565 |
| Status Epilepticus | disease | 28084627 |
