科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 喜树
英文名称: Common Camptotheac
拉丁名称: Camptotheca acuminata
使用部位: fruit or root
功用: To clear heat and resolve toxin, dissipate binds and disperse concretion, anticancer.
适用症: Acute leukemia, chronic leukemia, psoriasis, swollen liver and spleen due to bilharziosis, carcinoma of esophagus, carcinoma of cardia, carcinoma of intestine, carcinoma of liver, carcinoma of stomach, swelling of sores.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
7785-53-7 - (+)-alpha-Terpineol 442501
19685-09-7 - (19R)-19-Ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione 14440697
19685-09-7 10-羟基喜树碱 10-Hydroxycamptothecin 97226
19685-10-0 10-甲氧基喜树碱 10-Methoxycamptothecin 97283
2363-88-4 反式-2,4-癸二烯醛 2,4-Decadienal 5283349
21637-25-2 - 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 51402807
52845-07-5 - 2-Methylnonadecane 137081
1560-88-9 - 2-Methyloctadecane 15264
875-59-2 4′-羟基-2′-甲基苯乙酮 4-Hydroxy-2-methylacetophenone 70133
84567-08-8 4-羟基三尖杉碱 4-Hydroxycephalotaxine 158670

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 21445586
CASR CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR 3q13.33-q21.1 21445586

4. 相关疾病

疾病名称 疾病类型 参考文献
Liver Neoplasms, Experimental phenotype 21445586