科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 西川芎
英文名称: Chuanxiong rhizome, Szechuan lovage root
拉丁名称: Radix chuanxiong;Rhizoma Chuanxiong
使用部位: Ligusticum chuanxiong Hort.
功用: Treatment of menstrual disorders, amenorrhea, dysmenorrhea, abdominal pain with mass formation, pricking pain in the chest and costal regions, swelling and pain due to traumatic injury, headache, rheumatic arthralgia.
适用症: 1. Its active component, tetramethylpyrazine, can dilate the coronary artery and increase the coronary flow.2. Its aqueous solution and alcoholic infusion can lower blood pressure.3. Its alkaloids, ferulic acid and cnidilide are antispasmodics.4. Inhibiting the egrowth of intestinal gram-negative bacteria and skinfungi.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
106-22-9 β-香茅醇 - 8842
99-83-2 水芹烯 - 7460
18794-84-8 反式-β-金合欢烯 - 5281517
498-15-7 (1S)-(+)-3-蒈烯 (+)-3-Carene 443156
7785-70-8 (1R)-(+)-alpha-蒎烯 (+)-alpha-Pinene 82227
7785-53-7 - (+)-alpha-Terpineol 442501
66851-47-6 - 1,2-Benzenedi(carboxylic-14C)acid, dibutyl ester 171810
1454-85-9 1-十七烷醇 1-Heptadecanol 15076
111-87-5 1-辛醇 1-Octanol 957
629-76-5 十五醇 1-Pentadecanol 12397

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
TRPM8 LTRPC6; LTrpC-6; TRPP8; trp-p8 2q37.1 28396565

4. 相关疾病

疾病名称 疾病类型 参考文献
Diabetes Mellitus group 25411288
Glucose tolerance test phenotype 25411288
Insulin Resistance phenotype 25411288
Pain phenotype 28396565