1. 药材主信息
| 中文名称: | 天葵子 |
| 英文名称: | Muskroot-like Semiaquilegia Root |
| 拉丁名称: | Radix Semiaquilegiae |
| 使用部位: | - |
| 功用: | To remove toxic heat and promote the subsidence of swelling. |
| 适用症: | Treatment of carbuncles, boils and sores, mastitis, scrofula, venomous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 22527-23-7 | - | (+)-alpha-Santalene | 12315252 |
| 115-71-9 | - | (Z)-5-[(1S,3R)-2,3-dimethyl-3-tricyclo[2.2.1.02,6]heptanyl]-2-methylpent-2-en-1-ol | 24832102 |
| 71-36-3 | - | 1-Butanol | 263 |
| 629-96-9 | 1-二十醇 | 1-Eicosanol | 12404 |
| 28351-05-5 | 三十烷醇 | 1-Triacontanol | 68972 |
| 1423715-46-1 | - | 2(6H)-benzofuranone, 7,7a-dihydro-6-hydroxy-, (6R,7aR)- | 639165 |
| 67765-59-7 | Menisdaurilide | 2(6H)-Benzofuranone, 7,7a-dihydro-6-hydroxy-, (6S,7aR)- | 155054 |
| 89-86-1 | 2,4-二羟基苯甲酸 | 2,4-Dihydroxybenzoic acid | 1491 |
| 123-08-0 | 对羟基苯甲醛 | 4-Hydroxybenzaldehyde | 126 |
| 99-96-7 | 对羟基苯甲酸 | 4-Hydroxybenzoic acid | 135 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADORA2A | A2aR; ADORA2; RDC8 | 22q11.23 | 25772255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24486741 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24471788 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25754463 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31251107 |
| BAX | BCL2L4 | 19q13.33 | 24471788 |
| BAX | BCL2L4 | 19q13.33 | 25772255 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25772255 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 24471788 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 29723606 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 27933142 |
| Brain Ischemia | disease | 29426336 |
| Cancer cachexia | disease | 27493875 |
| Diabetes Mellitus, Experimental | disease | 30624028 |
| Diabetes Mellitus, Experimental | disease | 25754463 |
| Diabetic Retinopathy | disease | 31251107 |
| Hyperglycemia | disease | 24316371 |
| Hyperglycemia | disease | 30624028 |
| Hyperlipidemia | disease | 24316371 |
| Hypoxia | phenotype | 30396856 |
