1. 药材主信息
| 中文名称: | 桃儿七 |
| 英文名称: | Common Sinopodophyllm |
| 拉丁名称: | Podophyllum emodii |
| 使用部位: | root and rhizome |
| 功用: | To dispel wind and eliminate damp, quicken blood and relieve pain, relieve cough and dispel phlegm. |
| 适用症: | Wind-damp impediment pain, knocks and falls, menstrual disorder, dysmenorrhea, pain in stomach duct and abdomen, cough. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 477-49-6 | 鬼臼脂毒酮 | - | 443014 |
| 3590-93-0 | - | 4'-Demethyldeoxypodophyllotoxin | 160705 |
| 13270-61-6 | - | Flavylium, 3,3',4',5,5',7-hexahydroxy- | 128853 |
| 17434-18-3 | 苦鬼臼毒素 | Picropodophyllin | 72435 |
| 477-48-5 | 苦鬼臼脂毒酮 | Picropodopyllotoxone | 3083574 |
| 518-28-5 | 鬼臼毒素 | Podofilox | 10607 |
| 17187-73-4 | - | Podorhizol beta-D-glucoside | 443015 |
| 18651-67-7 | - | Sikkimotoxin | 3010626 |
| 70815-32-6 | - | Silandrin | 441663 |
| 42123-27-3 | 去氢鬼臼毒素 | Tetradehydropodophyllotoxin | 5316463 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27393705 |
| Casp14 | MICE; mini-ICE | 10|10 C1 | 25533330 |
| CLDN1 | CLD1; ILVASC; SEMP1 | 3q28 | 25533330 |
| FGFR1 | BFGFR; CD331; CEK; ECCL; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD; bFGF-R-1 | 8p11.23 | 25533330 |
| FN1 | CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF | 2q35 | 25749779 |
| FOSL1 | FRA; FRA1; fra-1 | 11q13.1 | 25533330 |
| FOSL2 | FRA2 | 2p23.2 | 25533330 |
| JUN | AP-1; AP1; c-Jun; cJUN; p39 | 1p32.1 | 25533330 |
| JUNB | AP-1 | 19p13.13 | 25533330 |
| JUND | AP-1 | 19p13.11 | 25533330 |
