1. 药材主信息
| 中文名称: | 娑罗子 |
| 英文名称: | Buckeye Seed |
| 拉丁名称: | Semen Aesculi |
| 使用部位: | ripe fruit without shell |
| 功用: | To regulate the flow of qi, normalize the stomach function and relieve pain. |
| 适用症: | Distending pain in chest and rib-side, distending pain in breast, dysmenorrhea, pain in stomach duct, pain in chest and abdomen. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 35323-91-2 | - | (+)-Epicatechin | 182232 |
| 28976-67-2 | - | (-)-beta-Curcumene | 14014430 |
| 6153-17-9 | - | (-)-beta-Phellandrene | 443161 |
| 1124-11-4 | 川芎嗪 | 2,3,5,6-Tetramethylpyrazine | 14296 |
| 1124-11-4 | 川芎嗪 | 2,3,5,6-Tetramethylpyrazine | 14296 |
| 644-30-4 | Α-姜黄烯 | alpha-Curcumene | 92139 |
| 62-53-3 | - | Aniline | 6115 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 24939-16-0 | 双去甲氧基姜黄素 | Bisdemethoxycurcumin | 5315472 |
| 79-92-5 | 莰烯 | Camphene | 6616 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCG2 | ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1 | 4q22.1 | 22300367 |
| ADAM17 | ADAM18; CD156B; CSVP; NISBD; NISBD1; TACE | 2p25.1 | 23548270 |
| AGER | RAGE; SCARJ1 | 6p21.32 | 22352842 |
| AGER | RAGE; SCARJ1 | 6p21.32 | 22452372 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 22258452 |
| Akr1b3 | ALR2; AR; Ahr-1; Ahr1; Akr1b1; Aldor1; Aldr1 | 6 14.87 cM|6 B1 | 22258452 |
| Akr1b7 | AR; Avdp; MVDP | 6 B1|6 14.95 cM | 22258452 |
| Akr1b8 | FR-1; Fgfrp; Fgrp | 6 B1|6 14.91 cM | 22258452 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21317920 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 22387197 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 31034781 |
| Adenocarcinoma | group | 25499851 |
| Adenomatous Polyposis Coli | disease | 20971552 |
| Alzheimer's Disease | disease | 30951849 |
| Alzheimer's Disease | disease | 30610916 |
| Anxiety | disease | 30542090 |
| Anxiety Disorders | group | 30542090 |
| Arthritis, Experimental | disease | 29306322 |
| Arthritis, Experimental | disease | 25836921 |
| Atherosclerosis | disease | 28739530 |
