1. 药材主信息
| 中文名称: | 生地黄 |
| 英文名称: | Fresh rehmannia root |
| 拉丁名称: | Radix Rehmanniae |
| 使用部位: | Rehmannia gultinosa Libosch. |
| 功用: | Treatment of exogenous heat invading at the nutritive and blood levels manifested as dry mouth and deep red tongue proper with scanty coating. Fresh rehmannia root (Shengdihuang) is used with Scrophularia (Xuanshen), Rhinoceros horn (Xijiao) and Ophiopogon root |
| 适用症: | 1. Its decoction exerts a protective effect on experimental hepatitis of mice induced by carbon tetrachloride.2. Gastric feeding or injection of its decoction, water infusion or alcoholic extract can lower the blood sugar level in rabbits (this result is controversial in the recent years).3. Intravenous injection of its extract exerts a hypertensive and diuretic effect in rabbits and dogs.4. Its alcoholic extract shortens the blood coagulation time in rabbits.5. Its water infusion inhibits the growth of some pathogenic fungi. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 1121-78-4 | 3-羟基-6-甲基吡啶 | 5-Hydroxy-2-methylpyridine | 14275 |
| 38072-88-7 | 蕨内酰胺 | 5-Methoxypyrrolidin-2-one | 181561 |
| 40222-77-3 | 6-(羟甲基)吡啶-3-醇 | 6-(Hydroxymethyl)pyridin-3-ol | 419490 |
| 7651-83-4 | 7-羟基异喹啉 | 7-Hydroxyisoquinoline | 459767 |
| 73-24-5 | 腺嘌呤 | Adenine | 190 |
| 41547-82-4 | 腺苷 | Adenosine | 60961 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 124151-33-3 | 松柏苷 | Coniferin | 5280372 |
| 82854-37-3 | 松果菊苷 | Echinacoside | 5281771 |
| 118-00-3 | 鸟苷 | Guanosine | 135398635 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 31378931 |
| ADORA2A | A2aR; ADORA2; RDC8 | 22q11.23 | 25772255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29284152 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24471788 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25754463 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31251107 |
| ATF6 | ACHM7; ATF6A | 1q23.3 | 28655643 |
| BAX | BCL2L4 | 19q13.33 | 23550774 |
| BAX | BCL2L4 | 19q13.33 | 24471788 |
| BAX | BCL2L4 | 19q13.33 | 25772255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 28616865 |
| Alzheimer's Disease | disease | 27933142 |
| Brain Ischemia | disease | 29426336 |
| Cancer cachexia | disease | 27493875 |
| Colitis | disease | 28655643 |
| Diabetes Mellitus, Experimental | disease | 29284152 |
| Diabetes Mellitus, Experimental | disease | 30624028 |
| Diabetes Mellitus, Experimental | disease | 25754463 |
| Diabetic Retinopathy | disease | 31251107 |
| Edema | phenotype | 28616865 |
