1. 药材主信息
| 中文名称: | 山楂 |
| 英文名称: | Chinese Hawthorn Equivalent plant: Crataegus pinna |
| 拉丁名称: | Crataegus pinnatifida |
| 使用部位: | fruit |
| 功用: | To fortify stomach and disperse food, move qi and dissipate stasis, lower cholesterol. |
| 适用症: | Hyperlipemia, myocardiac ischemia, angina pectoris, meat-type food accumulation, distention fullness in stomach duct, abdominal pain and diarrhea, amenorrhea due to blood stasis, postpartum stasis stagnation abdominal pain, stabbing pain in heart and abdomen, mounting qi . |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 617-94-7 | 2-苯基-2-丙醇 | - | 12053 |
| 4555-59-3 | - | (3R,3aR,5aR,5bR,7aR,9S,11aS,13aS,13bR)-9-methoxy-3a,5a,8,8,11a,13a-hexamethyl-3-propan-2-yl-2,3,4,5,5b,6,7,7a,9,10,11,13b-dodecahydro-1H-cyclopenta[a]chrysen-13-one | 101280159 |
| 40702-26-9 | 1,3,4-TRIMETHYL-3-CYCLOHEXEN-1-CARBOXALDEHYDE | 1,3,4-Trimethyl-3-cyclohexen-1-carboxaldehyde | 38621 |
| 1839-63-0 | - | 1,3,5-Trimethylcyclohexane | 35364 |
| 611-14-3 | 2-乙基甲苯 | 1-Ethyl-2-methylbenzene | 11903 |
| 2348-48-3 | - | 2-Methylbenzyl radical | 137549 |
| 592-27-8 | - | 2-Methylheptane | 11594 |
| 3221-61-2 | - | 2-Methyloctane | 18591 |
| 112-12-9 | 甲基正壬酮 | 2-Undecanone | 8163 |
| 16747-33-4 | - | 3-Ethyl-2,3-dimethylpentane | 28027 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27472952 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 22832932 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 27472952 |
| BIRC5 | API4; EPR-1 | 17q25.3 | 22832932 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 30250248 |
| Cognition Disorders | group | 21708244 |
| Colitis | disease | 25281414 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Diabetic Nephropathy | disease | 21195168 |
