1. 药材主信息
| 中文名称: | 日本女贞 |
| 英文名称: | Japanese Privet |
| 拉丁名称: | Ligustrum japonicum |
| 使用部位: | leaf |
| 功用: | To clear liver fire, resolve heat toxin. |
| 适用症: | Dizziness and dim vision, acute conjunctivitis, oral gan , tooth decay, innominate toxin swelling, burns and scalds. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 13289-20-8 | - | (3S,5S,8R,9S,10S,13R,14S,17R)-5,14-dihydroxy-3-[(2R,4S,5R,6R)-4-hydroxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde | 94348 |
| 96382-91-1 | 新女贞苷 | Neonuezhenide | 101720830 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24486195 |
| FGFR1 | BFGFR; CD331; CEK; ECCL; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD; bFGF-R-1 | 8p11.23 | 21145829 |
| HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | 14q23.2 | 28057028 |
| HMOX1 | HMOX1D; HO-1; HSP32; bK286B10 | 22q12.3 | 22214867 |
| NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | 2q31.2 | 22214867 |
| NOS2 | HEP-NOS; INOS; NOS; NOS2A | 17q11.2 | 24486195 |
| PDRG1 | C20orf126; PDRG | 20q11.21 | 28057028 |
| PRKAA1 | AMPK; AMPKa1 | 5p13.1 | 24486195 |
| PRKAA2 | AMPK; AMPK2; AMPKa2; PRKAA | 1p32.2 | 24486195 |
| PRKAB1 | AMPK; HAMPKb | 12q24.23 | 24486195 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinoma | group | 28057028 |
| Cardiomyopathies | group | 24486195 |
| Fatty Liver | disease | 21145829 |
| Liver Cirrhosis | disease | 21145829 |
| Nasopharyngeal carcinoma | disease | 28057028 |
| Nasopharyngeal Neoplasms | group | 28057028 |
| Non-alcoholic Fatty Liver Disease | disease | 21145829 |
