1. 药材主信息
| 中文名称: | 拳参 |
| 英文名称: | rhizome of Bistort |
| 拉丁名称: | Rhizoma Bistortae |
| 使用部位: | rhizome |
| 功用: | To remove toxic heat, to promote the subsidence of swelling, and to arrest bleeding. |
| 适用症: | Red dysentery, heat diarrhea, lung heat cough, swollen welling abscess, scrofula, mouth sore, tongue sores, blood ejection, spontaneous external bleeding, bleeding from hemorrhoids, poisonous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 89-80-5 | - | (+)-Menthone | 443159 |
| 85026-55-7 | 络思 | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(E)-3-phenylprop-2-enoxy]oxane-3,4,5-triol | 5280656 |
| 3687-48-7 | - | (3R)-oct-1-en-3-ol | 6992244 |
| 303-07-1 | 2,6-二羟基苯甲酸 | 2,6-Dihydroxybenzoic acid | 9338 |
| 589-98-0 | 3-辛醇 | 3-Octanol | 11527 |
| 106-68-3 | - | 3-Octanone | 246728 |
| 562-74-3 | 4-松油醇 | 4-Terpineol, (+/-)- | 11230 |
| 13186-19-1 | - | 6-O-Galloylglucose | 128839 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23684930 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| ATF2 | CRE-BP1; CREB-2; CREB2; HB16; TREB7 | 2q31.1 | 25787271 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30326282 |
| BGLAP | BGP; OC; OCN | 1q22 | 31943455 |
| BMP2 | BDA2; BMP2A; SSFSC | 20p12.3 | 25355404 |
| BNIP3 | NIP3 | 10q26.3 | 28838842 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26418626 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30326282 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alveolar Bone Loss | disease | 31943455 |
| Alzheimer's Disease | disease | 30447302 |
| Cerebral Ischemia | disease | 30486272 |
| Colitis | disease | 25281414 |
| Colitis | disease | 22677088 |
| Crohn Disease | disease | 22677088 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Diabetic Nephropathy | disease | 21195168 |
