1. 药材主信息
| 中文名称: | 秦艽 |
| 英文名称: | root of Largeleaf Gentian |
| 拉丁名称: | Radix Gentiae macrophyllae |
| 使用部位: | dried root |
| 功用: | To relieve rheumatic conditions, and to remove damp-heat. |
| 适用症: | Wind-damp impediment pain, hypertonicity of sinews and vessels, aching pain in joints, late afternoon tidal fever, child gan accumulation with fever. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 13877-91-3 | 罗勒烯 | - | 5281553 |
| 11019-08-2 | - | (5R-trans)-5,6-Dihydro-6-((2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)oxy)-5-vinyl-1H,3H-pyrano(3,4-c)pyran-1-one | 114428 |
| 99282-79-8 | 2-(CARBOXYMETHYL-AMINO)-4-CHLORO-BENZOIC ACID | 2-((Carboxymethyl)amino)-4-chlorobenzoic acid | 11107141 |
| 41679-97-4 | 7-O-甲基莫诺苷 | 7-O-Methyl morroniside | 127258930 |
| 70-47-3 | L-天冬酰胺 | Asparagine | 6267 |
| 55-21-0 | 苯甲酰胺 | Benzamide | 2331 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 67909-49-3 | 去氢吴茱萸碱 | Dehydroevodiamine | 9817839 |
| 90921-13-4 | 红白金花酸 | Erythrocentauric acid | 118726453 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | 5q32 | 26746354 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26746354 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26746354 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 26746354 |
| E2F1 | E2F-1; RBAP1; RBBP3; RBP3 | 20q11.22 | 31208440 |
| FOXM1 | FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT | 12p13.33 | 31208440 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 23032719 |
| JAK2 | JTK10; THCYT3 | 9p24.1 | 23032719 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 22461009 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 23032719 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Coronary Artery Disease | disease | 23025809 |
| Fatty Liver | disease | 23025809 |
| Hyperlipidemia | disease | 23025809 |
| Liver neoplasms | group | 31208440 |
| Liver neoplasms | group | 23032719 |
| melanoma | disease | 30305604 |
| Myocardial Reperfusion Injury | phenotype | 26746354 |
