1. 药材主信息
| 中文名称: | 千层塔 |
| 英文名称: | Serrate Clubmoss |
| 拉丁名称: | Huperzia serrata [Syn. Lycopodium serratum ] |
| 使用部位: | whole herb |
| 功用: | To abate fever, eliminate damp, disperse stasis, stanch bleeding, clear heat and resolve toxin. |
| 适用症: | Lung abscess, pneumonia, cor pulmonale, taxation damage and blood ejection, bleeding from hemorrhoids, vaginal discharge, knocks and falls, toxin swelling, hematuria, cold-damp ascites, enduring sores, scalds. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 102518-79-6 | - | (1R,9S,13Z)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one | 71308731 |
| 552325-16-3 | A-443654 | (2s)-1-(1h-Indol-3-Yl)-3-{[5-(3-Methyl-1h-Indazol-5-Yl)pyridin-3-Yl]oxy}propan-2-Amine | 10172943 |
| 24513-57-3 | 21-Episerratriol | 21-Episerratriol | 91895438 |
| 24513-51-7 | 3,21-二羟基-14-山芝烯-16-酮 | 3,21-Dihydroxy-14-serraten-16-one | 21589494 |
| 616-03-5 | 5-甲基乙内酰脲 | 5-Methylhydantoin | 69216 |
| 119188-49-7 | - | Huperzinine | 195296 |
| 20316-18-1 | - | Lycodine | 5462443 |
| 502-65-8 | 番茄红素 | Lycopene | 446925 |
| 110037-64-4 | - | N-Methylhuperzine B | 5489404 |
| 19637-58-2 | - | Serratanidine | 442499 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ACHE | ACEE; ARACHE; N-ACHE; YT | 7q22.1 | 21289607 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 21289607 |
| BAX | BCL2L4 | 19q13.33 | 21855911 |
| BIRC2 | API1; HIAP2; Hiap-2; MIHB; RNF48; c-IAP1; cIAP1 | 11q22.2 | 24606563 |
| BIRC3 | AIP1; API2; CIAP2; HAIP1; HIAP1; IAP-1; MALT2; MIHC; RNF49; c-IAP2 | 11q22.2 | 24606563 |
| BIRC5 | API4; EPR-1 | 17q25.3 | 24606563 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 24606563 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 21855911 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 21289607 |
| GSK3A | - | 19q13.2 | 21289607 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| adiposity | phenotype | 26614254 |
| Alzheimer's Disease | disease | 21289607 |
| Brain Ischemia | disease | 23045517 |
| Erythema | phenotype | 20854436 |
| Helicobacter Infections | group | 22178412 |
| Hypercholesterolemia | disease | 28412198 |
| Neuroblastoma | disease | 21289607 |
| Non-alcoholic Fatty Liver Disease | disease | 31947953 |
| Non-alcoholic Fatty Liver Disease | disease | 31790829 |
| Overweight | phenotype | 26614254 |
