1. 药材主信息
| 中文名称: | 女贞子 |
| 英文名称: | fruit of Glossy privet |
| 拉丁名称: | Fructus Ligustri lucidi |
| 使用部位: | Ligustru lucidu Ait. |
| 功用: | Treament of vertigo, tinnitus, weakness in the loins and knees, premature whitening of hair and impaired eyesight due to deficiency of yin of the liver and kidney. |
| 适用症: | 1. Its component oleanolic acid can prevent and relieve cyclophosphamide-induced leukocytopenia in mice.2. Enhancing the anoxia tolerance of mice under atmospheric pressure.3. Increasing coronary flow in rabbits in vitro.4. Relaxing adrenaline-induced vasocontricyion in rabbits in vitro.5. Lowering the level of blood lipid. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 35897-94-0 | 10-Hydroxyligstroside | 10-Hydroxyligstroside | 14756316 |
| 7084-24-4 | 矢车菊素-3-O-葡萄糖苷;花青素 | Cyanidin 3-glucoside chloride | 197081 |
| 552-58-9 | 圣草酚 | Eriodictyol | 440735 |
| 18719-76-1 | 氯化矢车菊素-3-O-芸香糖苷 | Keracyanin | 29231 |
| 117-39-5 | 槲皮素 | Quercetin | 5280343 |
| 10338-51-9 | 红景天苷 | Salidroside | 159278 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADORA2A | A2aR; ADORA2; RDC8 | 22q11.23 | 25772255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24486195 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24471788 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25754463 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31251107 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BAX | BCL2L4 | 19q13.33 | 24471788 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 27933142 |
| Brain Ischemia | disease | 29426336 |
| Cancer cachexia | disease | 27493875 |
| Carcinoma | group | 28057028 |
| Cardiomyopathies | group | 24486195 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Diabetes Mellitus, Experimental | disease | 30624028 |
