1. 药材主信息
| 中文名称: | 牛蒡子 |
| 英文名称: | achene of Great Burdock |
| 拉丁名称: | Fructus Arctii lappae |
| 使用部位: | fruit |
| 功用: | To dispel wind-heat and relieve cough, to promote eruption, to counteract toxicity, and to soothe sore throat. |
| 适用症: | Wind-heat common cold, cough with profuse phlegm, measles papules, wind papules, swelling pain in throat, epidemic parotitis, erysipelas, swollen welling abscess and sore toxin. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-30-9 | 花生酸 | - | 10467 |
| 112-31-2 | 癸醛 | - | 8175 |
| 616-16-0 | - | (+)-2-Methyl-1-butanol | 637572 |
| 89808-50-4 | 商陆皂苷 D | (2S,4aR,6aR,6aS,6bR,8aR,9R,10R,11S,12aR,14bS)-11-hydroxy-9-(hydroxymethyl)-2-methoxycarbonyl-2,6a,6b,9,12a-pentamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | 102004522 |
| 56283-68-2 | - | (3I(2),4I+/-,20I(2))-3,23-Dihydroxyolean-12-ene-28,29-dioic acid | 101297621 |
| 1730-91-2 | (S)-(+)-2-甲基丁酸 | (S)-2-methylbutanoic acid | 448893 |
| 6765-39-5 | 1-十七碳烯 | 1-Heptadecene | 23217 |
| 111-27-3 | 正己醇 | 1-Hexanol | 8103 |
| 629-76-5 | 十五醇 | 1-Pentadecanol | 12397 |
| 13360-61-7 | 1-十五碳烯 | 1-Pentadecene | 25913 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26148846 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26335809 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27836781 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| BAX | BCL2L4 | 19q13.33 | 27836781 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30326282 |
| BECN1 | ATG6; VPS30; beclin1 | 17q21.31 | 26148846 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 27756327 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Asthma | disease | 26335809 |
| Bone Resorption | phenotype | 31145860 |
| Diabetes | disease | 28707095 |
| Esophageal Neoplasms | group | 26603620 |
| Glucose Metabolism Disorders | group | 22095235 |
| Hyperglycemia | disease | 23471488 |
| Hyperglycemia | disease | 28707095 |
| Melanoma, Experimental | disease | 20840540 |
| Neoplasm Metastasis | phenotype | 20840540 |
| Pancreatic Neoplasm | disease | 27756327 |
