1. 药材主信息
| 中文名称: | 密蒙花 |
| 英文名称: | flower of Pale Butterflybush |
| 拉丁名称: | Flos Buddlejae |
| 使用部位: | flower |
| 功用: | To remove heat, replenish the liver and clear the eye of corneal opacity. |
| 适用症: | Red eyes with gall, delacrimation and photophobia, liver vacuity dim vision, dim vision, malaria. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 1257-08-5 | 表儿茶素没食子酸酯 | (-)-Epicatechin gallate | 107905 |
| 495-78-3 | - | 2-Hydroxybenzenepropanoic acid | 873 |
| 480-44-4 | 金合欢素;刺槐素 | Acacetin | 5280442 |
| 104-46-1 | 反式茴香脑 | Anethole | 637563 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 578-74-5 | 芹菜素-7-O-β-D-吡喃葡萄糖苷;大波斯菊苷 | Apigetrin | 5280704 |
| 64274-28-8 | - | Aucubigenin | 163040 |
| 479-98-1 | 桃叶珊瑚苷 | Aucubin | 91458 |
| 84744-28-5 | - | Calceolarioside A | 5273566 |
| 57-88-5 | 胆固醇 | Cholesterol | 5997 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 31378931 |
| AHR | RP85; bHLHe76 | 7p21.1 | 30831189 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29284152 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| ATF6 | ACHM7; ATF6A | 1q23.3 | 28655643 |
| BAX | BCL2L4 | 19q13.33 | 23550774 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 23550774 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Alzheimer's Disease | disease | 30578827 |
| Atrial Fibrillation | disease | 21906601 |
| Blood Pressure | phenotype | 28143892 |
| Brain Ischemia | disease | 30239332 |
| Cardiac fibrosis | disease | 31504241 |
| Chromosome Aberrations | group | 23701745 |
| Colitis | disease | 28655643 |
| Diabetes Mellitus, Experimental | disease | 22882757 |
| Diabetes Mellitus, Experimental | disease | 29284152 |
