科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 荔枝草
英文名称: Common Sage
拉丁名称: Salvia plebeia
使用部位: aerial parts
功用: To clear heat and resolve toxin, cool blood and dissipate stasis, disinhibit water and disperse edema.
适用症: Common cold with fever, swelling pain in throat, lung heat cough, hemoptysis, blood ejection, hematuria, flooding and spotting, bleeding from hemorrhoids, nephritis with edema, white turbidity, dysentery, swelling toxin of welling abscess and sore, eczema titillation, knocks and falls, snake or insect bites.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
99-50-3 原儿茶酸 3,4-Dihydroxybenzoic acid 72
520-11-6 泽兰黄酮 Eupafolin 5317284
1447-88-7 高车前素 Hispidulin 5281628
569-90-4 假荆芥属苷 Nepitrin 120742

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 20840540
BAX BCL2L4 19q13.33 30326282
BCL2 Bcl-2; PPP1R50 18q21.33 30326282
BCL2L11 BAM; BIM; BOD 2q13 31817696
CASP3 CPP32; CPP32B; SCA-1 4q35.1 30326282
CASP8 ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 2q33.1 30326282
CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 1p36.21 30326282
IL10 CSIF; GVHDS; IL-10; IL10A; TGIF 1q32.1 26603620
IL1B IL-1; IL1-BETA; IL1F2; IL1beta 2q14.1 26603620
MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 16q12.2 20840540

4. 相关疾病

疾病名称 疾病类型 参考文献
Esophageal Neoplasms group 26603620
Melanoma, Experimental disease 20840540
Neoplasm Metastasis phenotype 20840540