1. 药材主信息
| 中文名称: | 苦瓜 |
| 英文名称: | Balsampear |
| 拉丁名称: | Momordica charantia |
| 使用部位: | fruit |
| 功用: | To dispel summerheat, brighten eyes, resolve toxin. |
| 适用症: | Summerheat-heat vexation and thirst, diabetes mellitus, painful red eyes, dysentery, swelling toxin of sore and welling abscess. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 105279-10-5 | 柑属苷B | (2S,3R,4S,5S,6R)-2-[4-[1,3-Dihydroxy-2-[4-[(E)-3-hydroxyprop-1-enyl]-2,6-dimethoxyphenoxy]propyl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 11972318 |
| 372-75-8 | L-瓜氨酸 | Citrulline | 9750 |
| 2623-91-8 | D-2-氨基丁酸 | D-2-Aminobutyric acid | 439691 |
| 25990-10-7 | 多聚半乳糖醛酸 | D-Galacturonic Acid | 439215 |
| 104086-74-0 | - | Galanal A | 3050416 |
| 502-65-8 | 番茄红素 | Lycopene | 446925 |
| 152-93-2 | 蚕豆苷 | Vicine | 135413566 |
| 57800-41-6 | - | Vignafuran | 441958 |
| 14356-51-5 | (3BETA)-3-羟基-1-氧代-齐墩果-12-烯-28-酸 | Virgatic acid | 14489125 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| BAX | BCL2L4 | 19q13.33 | 21855911 |
| BIRC2 | API1; HIAP2; Hiap-2; MIHB; RNF48; c-IAP1; cIAP1 | 11q22.2 | 24606563 |
| BIRC3 | AIP1; API2; CIAP2; HAIP1; HIAP1; IAP-1; MALT2; MIHC; RNF49; c-IAP2 | 11q22.2 | 24606563 |
| BIRC5 | API4; EPR-1 | 17q25.3 | 24606563 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 24606563 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 21855911 |
| IFNG | IFG; IFI | 12q15 | 31790829 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 24606563 |
| KEAP1 | INrf2; KLHL19 | 19p13.2 | 32014502 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 22889596 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| adiposity | phenotype | 26614254 |
| Brain Ischemia | disease | 23045517 |
| Erythema | phenotype | 20854436 |
| Helicobacter Infections | group | 22178412 |
| Hypercholesterolemia | disease | 28412198 |
| Non-alcoholic Fatty Liver Disease | disease | 31947953 |
| Non-alcoholic Fatty Liver Disease | disease | 31790829 |
| Overweight | phenotype | 26614254 |
| Pediatric Obesity | disease | 26614254 |
| Peritonitis | disease | 22889596 |
