1. 药材主信息
| 中文名称: | 莪术 |
| 英文名称: | Zedoray Rhizome |
| 拉丁名称: | Rhizoma Curcumae |
| 使用部位: | - |
| 功用: | To promote the flow of qi and eliminate blood stasis with strong effect, and to relieve pain by removing the stagnation of undigested food. |
| 适用症: | 1. Its volatile oil and its components curcumenol, curdione and B-elemene destroy directly the Ehrlich-Ascites tumor and leukemia615 in mice. 2. Promoting phagocytosis of monocytes. 3. Dilating peripheral blood vessels, inhibiting aggregation of thrombocytes and thrombosis, and improving microcirculation. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 483-76-1 | (+)-DELTA-CADINENE | - | 441005 |
| 502-61-4 | α－法呢烯 | - | 5281516 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 489-39-4 | (+)-Aromadendrene | (+)-Aromadendrene | 11095734 |
| 19902-08-0 | - | (+)-beta-Pinene | 10290825 |
| 5794-03-6 | - | (+)-Camphene | 92221 |
| 19431-84-6 | 莪术烯醇 | (+)-Curcumenol | 167812 |
| 20296-50-8 | - | (-)-3-Carene | 442461 |
| 464-48-2 | - | (-)-Camphor | 444294 |
| 10408-16-9 | - | (-)-Sabinene | 11051711 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCG2 | ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1 | 4q22.1 | 22300367 |
| ADAM17 | ADAM18; CD156B; CSVP; NISBD; NISBD1; TACE | 2p25.1 | 23548270 |
| AGER | RAGE; SCARJ1 | 6p21.32 | 22352842 |
| AGER | RAGE; SCARJ1 | 6p21.32 | 22452372 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 22258452 |
| Akr1b3 | ALR2; AR; Ahr-1; Ahr1; Akr1b1; Aldor1; Aldr1 | 6 14.87 cM|6 B1 | 22258452 |
| Akr1b7 | AR; Avdp; MVDP | 6 B1|6 14.95 cM | 22258452 |
| Akr1b8 | FR-1; Fgfrp; Fgrp | 6 B1|6 14.91 cM | 22258452 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21317920 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 22387197 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 31034781 |
| Adenocarcinoma | group | 25499851 |
| Adenomatous Polyposis Coli | disease | 20971552 |
| Alzheimer's Disease | disease | 30951849 |
| Alzheimer's Disease | disease | 30610916 |
| Anxiety | disease | 30542090 |
| Anxiety Disorders | group | 30542090 |
| Arthritis, Experimental | disease | 29306322 |
| Arthritis, Experimental | disease | 25836921 |
| Atherosclerosis | disease | 28739530 |
