1. 药材主信息
| 中文名称: | 地耳草 |
| 英文名称: | all - grass of Japanese St. Johnswort |
| 拉丁名称: | Herba Hyperici Japonici |
| 使用部位: | whole herb |
| 功用: | 1.To deprive dampness and relieve jaundice. 2. To clear away heat and toxic material. 3. To promote blood circulation and relieve edema. |
| 适用症: | Damp-heat jaundice, diarrhea, dysentery, intestinal welling abscess, pulmonary welling abscess, swelling toxin of welling abscess and boil, nipple moth, mouth sore, red eyes with gall, poisonous snake bite, knocks and falls. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 112-31-2 | 癸醛 | - | 8175 |
| 495-61-4 | (-)-β-bisabolene | - | 10104370 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 515-69-5 | - | (+)-Epi-alpha-bisabolol | 1201551 |
| 3687-48-7 | - | (3R)-oct-1-en-3-ol | 6992244 |
| 95-50-1 | - | 1,2-Dichlorobenzene | 7239 |
| 5084-31-1 | 1,3,5,6-四羟基呫吨酮 | 1,3,5,6-Tetrahydroxyxanthone | 5479774 |
| 6732-85-0 | 1,3,5-三羟基咕吨酮 | 1,3,5-Trihydroxyxanthone | 5281663 |
| 504-63-2 | 1,3-丙二醇 | 1,3-Propanediol | 10442 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 21445586 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27017346 |
| BAK1 | BAK; BAK-LIKE; BCL2L7; CDN1 | 6p21.31 | 24680709 |
| BAX | BCL2L4 | 19q13.33 | 24680709 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30326282 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 29247826 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30326282 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 30326282 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Asthma | disease | 27185659 |
| Atherosclerosis | disease | 27017346 |
| Brain Neoplasms | group | 20883786 |
| Bronchial Hyperreactivity | disease | 27185659 |
| Cerebellar Neoplasms | group | 20883786 |
| Colitis | disease | 25281414 |
| Colitis | disease | 29945292 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
