科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 寸冬
英文名称: Root of Dwarf Lilyturf.
拉丁名称: Radix Ophiopogonis
使用部位: Ophiopogon japonicus ( Thunb. Ker-Gawl.
功用: Treament of dry cough, phthisical cough, thirst due to impairment of body fluid, fidgetness and insomnia, diabetes caused by internal heat, constipation, diphtheria.
适用症: 1. Relieving leucopenia in mice induced by cyclophosphamide and radiation sickness in dogs.2. Increasing anoxia tolerance in experimental animals under atmospheric pressure.3. Increasing coronary flow and improving myocardial contractility in guinea-pigs.4. Decreasing the level of blood sugar.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
74805-90-6 甲基麦冬高黄酮A Methylophiopogonone A 10065830
74805-89-3 甲基麦冬黄酮B Methylophiopogonone B 23259413
75239-63-3 麦冬二氢高异黄酮A Ophiopogonanone A 9996586
125150-67-6 麦冬皂苷D Ophiopogonin D 46173859

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
KLF3 BKLF 4p14 31196982
STAT3 ADMIO; ADMIO1; APRF; HIES 17q21.2 30413072

4. 相关疾病

疾病名称 疾病类型 参考文献
Body Weight phenotype 29084766
Dysbiosis phenotype 29084766
Hyperglycemia disease 29084766
Hyperlipidemia disease 29084766
Insulin Resistance phenotype 29084766
Non-Small Cell Lung Carcinoma disease 30413072
Osteoporosis disease 31196982