1. 药材主信息
| 中文名称: | 刺五加 |
| 英文名称: | Manypr ickle Acanthopana x |
| 拉丁名称: | Acanthopanax senticosus [Syn. Eleutherococcus sent |
| 使用部位: | root and rhizome |
| 功用: | To boost qi and fortify spleen, supplement kidney and quiet spirit, increase appetite. |
| 适用症: | Spleen-kidney yang vacuity, vacuity and hypodynamia, inappetence, aching in lumbus and knees, insomnia and frequent dreaming. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 29106-36-3 | 松脂素二甲醚 | (+)-Eudesmin | 73117 |
| 17605-67-3 | 岩藻甾醇 | (24E)-24-N-Propylidenecholesterol | 5281328 |
| 530-55-2 | 2,6-二甲基-1,4-苯醌 | 2,6-Dimethoxyquinone | 68262 |
| 533-31-3 | 芝麻酚 | 3,4-Methylenedioxyphenol | 68289 |
| 1110-58-3 | - | 7-(8-Formyl-1,7-dihydroxy-5-isopropyl-6-methoxy-3-methyl-2-naphthyl)-2,8-dihydroxy-4-isopropyl-3-methoxy-6-methyl-naphthalene-1-carbaldehyde | 375713 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 483-91-0 | 异嗪皮啶7-O-beta-D-葡萄糖苷 | Calycanthoside | 5318566 |
| 114912-35-5 | 刺五加皂苷 D1 | Ciwujianoside D1 | 163951 |
| 218901-26-9 | 刺五加酮 | Ciwujiatone | 5315944 |
| 62770-67-6 | - | Clausarin | 5315945 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| IKBKB | IKK-beta; IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB | 8p11.21 | 22168157 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 22168157 |
| NFKBIA | EDAID2; IKBA; MAD-3; NFKBI | 14q13.2 | 22168157 |
| RELA | CMCU; NFKB3; p65 | 11q13.1 | 22168157 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Pseudomonas Infections | group | 22020237 |
| Septic Shock | phenotype | 22020237 |
| Shock, Cardiogenic | phenotype | 22020237 |
