科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 炒枳壳
英文名称: Prepared fruit of Seville orange
拉丁名称: Fructus Aurantii Preparata
使用部位: Citrus aurantiu L.
功用: Treatment of distension and pain in the chest and hypochondriac regions due to stagnation of qi, indigestion with retention of phlegm and fluid, gastroptosis, prolapse of the rectum, prolapse of the uterus.
适用症: Treatment of distension and pain in the chest and hypochondriac regions due to stagnation of qi, indigestion with retention of phlegm and fluid, gastroptosis, prolapse of the rectum, prolapse of the uterus.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
10236-47-2 柚皮苷 Naringin 442428

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 25047426
AURKA AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7 20q13.2 25047426
BAX BCL2L4 19q13.33 25047426
BCL2 Bcl-2; PPP1R50 18q21.33 25047426
CASP3 CPP32; CPP32B; SCA-1 4q35.1 25047426
CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 1p36.21 25047426
CTNNB1 CTNNB; EVR7; MRD19; NEDSDV; armadillo 3p22.1 25047426
CYC1 MC3DN6; UQCR4 8q24.3 25047426
GSK3B - 3q13.33 25047426
JUN AP-1; AP1; c-Jun; cJUN; p39 1p32.1 25047426

4. 相关疾病

疾病名称 疾病类型 参考文献
Carcinogenesis phenotype 25047426
Colonic Neoplasms group 25047426