科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 北五味
英文名称: fruit of Chinese Nmagnoliavine
拉丁名称: Fructus Schiandrae
使用部位: Schisandra chinensis (Turcz. ) Baill
功用: Treatment of chronic cough and asthma, nocturnal emission, spermatorrhea, enuresis, frequent urination, protracted diarrhea, spontaneous sweating, night sweating, impairment of body fluid with thirst, shortness of breath and feeble pulse, diabetes caused by internal heat, palpitation and insomnia.
适用症: 1. Its decoction exerts bacteriostatic effect on Pseudomonas aeruginosa (1:128), Staphylococcus aureus (1:64), Flexner's bacillus (1:32) and typhoid bacillus (1:8) in vitro.2. Schizandrin, one of its active components, can protect the liver from damage.3. Enhancing lymphocyte-blastogenesis rate.4. Cardiotonic and sedative.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
18794-84-8 反式-β-金合欢烯 - 5281517
18794-84-8 反式-β-金合欢烯 - 5281517
136040-43-2 五内脂 - 14844611
495-61-4 (-)-β-bisabolene - 10104370
13877-91-3 罗勒烯 - 5281553
99-83-2 水芹烯 - 7460
502-61-4 α-法呢烯 - 5281516
498-15-7 (1S)-(+)-3-蒈烯 (+)-3-Carene 443156
7785-70-8 (1R)-(+)-alpha-蒎烯 (+)-alpha-Pinene 82227
7785-53-7 - (+)-alpha-Terpineol 442501

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
CNR2 CB-2; CB2; CX5 1p36.11 31883107
TRPM8 LTRPC6; LTrpC-6; TRPP8; trp-p8 2q37.1 28396565

4. 相关疾病

疾病名称 疾病类型 参考文献
Pain phenotype 28396565