科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 巴豆
英文名称: Croton Fruit
拉丁名称: Fructus Crotonis
使用部位: dried seed
功用: 1. To drain accumulated cold downward; 2. To transform water and reduce edema; 3. To resolve phlegm and benefit throat
适用症: Distention fullness and sudden pain in chest and a bdomen, fecal stoppage, diarrhea and dysentery, edema and enlarged abdomen, phlegm-rheum asthma fullness, throat wind, throat impediment, concretion and conglomeration, welling abscess and flat abscess, malign sore and scab lichen.
毒副作用: Extremely Toxic

2. 相关成分

CAS号 中文名称 英文名称 参考文献
506-30-9 花生酸 - 10467
506-30-9 花生酸 - 10467
142878-33-9 - 1,6-Dihydroxy-2,4-dimethoxyanthraquinone 126726
142878-32-8 - 1,6-Dihydroxy-2-methoxyanthraquinone 132521
6268-09-3 1-羟基-2-甲基蒽醌 1-Hydroxy-2-methylanthraquinone 160817
129-43-1 1-羟基蒽醌 1-Hydroxyanthraquinone 8512
1120-36-1 1-十四烯 1-Tetradecene 14260
250268-55-4 - 12-O-Acetylphorbol-13-tigliate 6451045
250268-56-5 - 12-O-Decanoylphorbol-13-(2-methylbutyrate) 476547
250268-57-6 - 12-O-Tigloylphorbol-13-(2-methylbutyrate) 6451046

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
DGKD DGK-delta; DGKdelta; dgkd-2 2q37.1 28707095
GCG GLP-1; GLP1; GLP2; GRPP 2q24.2 23471488
PGD 6PGD 1p36.22 27270429

4. 相关疾病

疾病名称 疾病类型 参考文献
Diabetes disease 28707095
Hyperglycemia disease 23471488
Hyperglycemia disease 28707095
leukemia disease 27270429